This is more classical and common. The ulcer penetrates deep into the mucosa. More than 95% occur in the first part of the duodenum. About 60% of ulcers recur within one year and 90% within two years.
* Cause
* Symptoms
* Diagnosis
* Medical Management
Causative factors
These are not known for sure. The number of acid-secreting cells is high, with greater outpouring of acid. Excessive acid flow is consequential, in comparison to gastric ulcer where defective mucosal resistance is the cause. Genetic factors appear to be important. Alcohol and cigarettes are potent causative and aggravating factors. Others are chronic usage of painkiller drugs, poor lifestyle, a bacteria known as helicobacter pylori found in a number of patients with DU, skipping meals (which allows acid to irritate the lining, the outflow being aggravated by stress on an empty stomach) and, most important, the mind. Stress produces and aggravates duodenal ulcer in any situation. Of this there is no doubt. All patients experience increase in pain with stress.
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